Fine-tuning lasers to destroy
blood-borne diseases like AIDS
激光微调摧毁血源性传染病-爱滋病
来源:www.iop.org
翻译:Duli@语际翻译
Physicists in Arizona State
University have designed a
revolutionary laser technique
which can destroy viruses and
bacteria such as AIDS without
damaging human cells and may
also help reduce the spread of
hospital infections such as
MRSA.
亚利桑那州立大学的物理学家已经设计出了一种革命性的激光技术,它可以消灭病毒和细菌(例如爱滋病)而不损害人体细胞,也可能有助于减少医院内感染病原菌的传播,如MRSA(甲氧西林耐药金黄色葡萄球菌)。
The research, published on
Thursday November 1 in the
Institute of Physics’: Condensed
Matter, discusses how pulses
from an infrared laser can be
fine-tuned to discriminate
between problem microorganisms
and human cells.
这项研究于11月1日星期四发表在物理研究所学报《凝聚态物质》上,研究微调从红外激光发出的脉冲,以区分病原微生物和人类细胞。
Current laser treatments such
as UV are indiscriminate and can
cause ageing of the skin, damage
to the DNA or, at worst, skin
cancer, and are far from 100 per
cent effective.
目前激光疗法(如紫外线),(对波长)是不加选择的,因此引起皮肤老化,DNA损伤甚至皮肤癌,远远未达到百分之百有效的程度。
Femtosecond laser pulses,
through a process called
Impulsive Stimulated Raman
Scattering (ISRS), produces
lethal vibrations in the protein
coat of microorganisms, thereby
destroying them. The effect of
the vibrations is similar to
that of high-pitched noise
shattering glass.
飞秒激光脉冲,通过一个称之为冲击受激拉曼散射(ISRS)的过程,在微生物的蛋白质外壳产生致命的振动,从而摧毁他们。振动的作用与高声调噪声粉碎玻璃相类似。
The physicists in Arizona have
undertaken experiments to show
that the coherent vibrations
excited by infrared lasers with
carefully selected wavelengths
and pulse widths do no damage to
human cells, most likely because
of the different structural
compositions in the protein
coats of human cells vis a vis
bacteria and viruses.
亚利桑那大学的物理学家的实验表明,这种红外激光器激发的有着精选的波长和脉冲宽度的连续振动对人体细胞没有什么损害,这最有可能是因为人类细胞与细菌、病毒的外衣蛋白质有着不同的结构组成。
Professor K. T. Tsen from
Arizona State University said,
“Although it is not clear at the
moment why there is a large
difference in laser intensity
for inactivation between human
cells and microorganisms such as
bacteria and viruses, the
research so far suggests that
ISRS will be ready for use in
disinfection and could provide
treatments against some of the
worst, often drug-resistant,
bacterial and viral pathogens.”
亚利桑那州立大学的K. T.
Tsen教授说,“虽然目前并不清楚为什么灭活人体细胞和微生物(如细菌和病毒)的激光强度有那么大的差异,到目前为止,研究显示ISRS可用于消毒,并能用于对付一些最厉害的,而且往往具有抗药性的细菌和病毒的病原体。
”
Femtosecond lasers could find
immediate application in
hospitals as a way to disinfect
blood supply or biomaterials and
for the treatment of blood-borne
diseases such as AIDS and
Hepatitis.
飞秒激光器,可以立即应用到医院中,用作血液供应消毒或用作生物材料治疗血源性传染病,如爱滋病和肝炎。
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